Optimization of the Chemical Composition of the Bioresorbtive Magnesium Alloy Used in Osteosynthesis

Processy litʹâ, 2019, Tom 133, №1, p.61-69

Authors

  • M. D. Aikin Zaporizhzhya National Technical University, Zaporizhia
  • V. A. Shalomeev Zaporizhzhya National Technical University, Zaporizhia
  • V. N. Chorniy* *Zaporizhzhya State Medical University, Zaporizhia

DOI:

https://doi.org/10.15407/plit2019.1.61-69

Keywords:

alloying elements, experimental design, tensile strength, relative extension, chemical composition, optimization

Abstract

Received 10.12.2018

UDK 669.721.5

One of the most promising materials for the production of implants are Mg−Zr−Nd alloys. They are bioinert, biocompatible and have the biodegradation ability, but their use in osteosynthesis is limited due to their insufficient mechanical properties after prolonged exposure to the internal environment of the body. The effect of the main alloying elements (Zr, Nd, Zn) on the mechanical properties of the Mg–Zr–Nd alloy was studied using the experimental design. Optimization of the chemical composition of the alloy increased the tensile strength (σB ) and elongation at break (δ). Animal experiments showed the absence of the toxicological effect of the degradation products of the developed magnesium alloy on a living organism. The study of the processes of bone regeneration of the studied animals gave a positive result.

Author Biographies

M. D. Aikin, Zaporizhzhya National Technical University, Zaporizhia

Postgraduate Student

V. A. Shalomeev, Zaporizhzhya National Technical University, Zaporizhia

Doctor of Technical Sciences, Professor

V. N. Chorniy*, *Zaporizhzhya State Medical University, Zaporizhia

Candidate of Medical Sciences, Assistant Professor

References

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Published

12-01-2019

How to Cite

Aikin М. Д. ., Shalomeev В. A. ., & Chorniy* В. . (2019). Optimization of the Chemical Composition of the Bioresorbtive Magnesium Alloy Used in Osteosynthesis: Processy litʹâ, 2019, Tom 133, №1, p.61-69. Casting Processes, 133(1), 61–69. https://doi.org/10.15407/plit2019.1.61-69

Issue

Casting processes №1 (133) 2019

Section

NEW CASTING MATERIALS

License

Copyright (c) 2019 М. Д. Айкін, В. A. Шаломєєв, В.М. Чорний*

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.